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Abstract One possible solution against the accumulation of petrochemical plastics in natural environments is to develop biodegradable plastic substitutes using natural components. However, discovering all-natural alternatives that meet specific properties, such as optical transparency, fire retardancy and mechanical resilience, which have made petrochemical plastics successful, remains challenging. Current approaches still rely on iterative optimization experiments. Here we show an integrated workflow that combines robotics and machine learning to accelerate the discovery of all-natural plastic substitutes with programmable optical, thermal and mechanical properties. First, an automated pipetting robot is commanded to prepare 286 nanocomposite films with various properties to train a support-vector machine classifier. Next, through 14 active learning loops with data augmentation, 135 all-natural nanocomposites are fabricated stagewise, establishing an artificial neural network prediction model. We demonstrate that the prediction model can conduct a two-way design task: (1) predicting the physicochemical properties of an all-natural nanocomposite from its composition and (2) automating the inverse design of biodegradable plastic substitutes that fulfils various user-specific requirements. By harnessing the model’s prediction capabilities, we prepare several all-natural substitutes, that could replace non-biodegradable counterparts as exhibiting analogous properties. Our methodology integrates robot-assisted experiments, machine intelligence and simulation tools to accelerate the discovery and design of eco-friendly plastic substitutes starting from building blocks taken from the generally-recognized-as-safe database. 

Amber is a system-on-chip (SoC) with a coarse-grained reconfigurable array (CGRA) for acceleration of dense linear algebra applications, such as machine learning (ML), image processing, and computer vision. It is designed using an agile accelerator-compiler co-design flow; the compiler updates automatically with hardware changes, enabling continuous application-level evaluation of the hardware-software system. To increase hardware utilization and minimize reconfigurability overhead, Amber features the following: 1) dynamic partial reconfiguration (DPR) of the CGRA for higher resource utilization by allowing fast switching between applications and partitioning resources between simultaneous applications; 2) streaming memory controllers supporting affine access patterns for efficient mapping of dense linear algebra; and 3) low-overhead transcendental and complex arithmetic operations. The physical design of Amber features a unique clock distribution method and timing methodology to efficiently layout its hierarchical and tile-based design. Amber achieves a peak energy efficiency of 538 INT16 GOPS/W and 483 BFloat16 GFLOPS/W. Compared with a CPU, a GPU, and a field-programmable gate array (FPGA), Amber has up to 3902x, 152x, and 107x better energy-delay product (EDP), respectively. 

Abstract We introduce a notion of ‘cross-section continuity’ as a criterion for the viability of definitions of angular momentum, J , at null infinity: If a sequence of cross-sections, , of null infinity converges uniformly to a cross-section , then the angular momentum, J n , on should converge to the angular momentum, J , on . The Dray–Streubel (DS) definition of angular momentum automatically satisfies this criterion by virtue of the existence of a well defined flux associated with this definition. However, we show that the one-parameter modification of the DS definition proposed by Compere and Nichols—which encompasses numerous other alternative definitions—does not satisfy cross-section continuity. On the other hand, we prove that the Chen–Wang–Yau definition does satisfy the cross-section continuity criterion.